PTEN -| PIP3
PI3K -> PIP3
PIP2 -> PIP3
GF -> GFR
IAP -| Cas7
Cas8 -> Cas7
APC -> Cas7
p53 -> PTEN
TNF -> TNFR2
GFR -> PIP2
p53 -> Apaf1
RIP -> TRAF2
TNFR2 -> TRAF2
TRADD -> TRAF
TNF -> TNFR1
RIP -> MEKK1
AKT -> IKK
NIK -> IKK
A20 -| IKK
TNFR1 -> TRADD
TRAF -> cFLIP
BID -> Mito
BclX -| Mito
IKK -| IkB
NFkB -> IkB
TRADD -> RIP
JNKK -> JNK
TRAF2 -> NIK
Cas3 -> DNADamageEvent
AKT -| JNKK
MEKK1 -> JNKK
IkB -| NFkB
PIP3 -> AKT
NFkB -> BclX
BAD -| BclX
p53 -| BclX
NFkB -> A20
IAP -| Cas3
Cas8 -> Cas3
Cas6 -> Cas3
APC -> Cas3
cFLIP -| Cas8
FADD -> Cas8
Cas6 -> Cas8
DNADamageEvent -> Apoptosis
Cas3 -> Cas6
IAP -| Cas6
Mdm2 -| p53
DNADamageEvent -> p53
JNK -> p53
GFR -> PI3K
AKT -| BAD
p53 -> BAD
Cas9 -> APC
IAP -| APC
Mito -> APC
Apaf1 -> APC
AKT -> Mdm2
p53 -> Mdm2
Cas7 -> Cas12
Cas3 -| IAP
NFkB -> IAP
Mito -| IAP
Cas6 -> IAP
AKT -| Cas9
Cas3 -> Cas9
IAP -| Cas9
Cas12 -> Cas9
p53 -> BID
Cas8 -> BID
JNK -> BID
BclX -| BID
TRADD -> FADD
$A20: NFkB
$AKT: PIP3
$APC: ((Cas9 & (Mito & Apaf1)) & !IAP)
$Apaf1: p53
$Apoptosis: DNADamageEvent
$BAD: (p53 & !AKT)
$BID: (((JNK & p53) & !BclX) | ((Cas8 & p53) & !BclX))
$BclX: (NFkB & !(p53 | BAD))
$Cas12: Cas7
$Cas3: (((APC & !IAP) | (Cas6 & !IAP)) | (Cas8 & !IAP))
$Cas6: (Cas3 & !IAP)
$Cas7: ((Cas8 & !IAP) | (APC & !IAP))
$Cas8: ((FADD & !cFLIP) | (Cas6 & !cFLIP))
$Cas9: ((Cas12 & !(AKT | IAP)) | (Cas3 & !(AKT | IAP)))
$DNADamageEvent: Cas3
$FADD: TRADD
$GFR: GF
$IAP: (NFkB & !((Cas3 & Cas6) | Mito))
$IKK: ((NIK & !A20) | (AKT & !A20))
$IkB: (NFkB & !IKK)
$JNK: JNKK
$JNKK: (MEKK1 & !AKT)
$MEKK1: RIP
$Mdm2: (p53 | AKT)
$Mito: (BID & !BclX)
$NFkB: !IkB
$NIK: TRAF2
$PI3K: GFR
$PIP2: GFR
$PIP3: ((PI3K & PIP2) & !PTEN)
$PTEN: p53
$RIP: TRADD
$TNFR1: TNF
$TNFR2: TNF
$TRADD: TNFR1
$TRAF: TRADD
$TRAF2: (TNFR2 | RIP)
$cFLIP: TRAF
$p53: ((DNADamageEvent & !Mdm2) | (JNK & !Mdm2))